Revealed: The Vaccines Induce Cellular Ageing

ER Editor: See also this piece by Dr. Mike Williams, titled

Are Covid Vaccines Engineered to Disable Our Immune Systems?


Revealed: Vaccine Induced Cellular Ageing


21st Century Wire

In prior articles we discussed the increased risk of SARS-CoV-2 infection after Covid vaccination and introduced concepts of immune tolerance and immune training. In this article I want to introduce the topic of cellular senescence, specifically as it relates to Covid vaccination.

From Cellular Senescence: What, Why, and How we learn:

Cellular senescence is a process that results from a variety of stresses and leads to a state of irreversible growth arrest. Senescent cells accumulate during aging and have been implicated in promoting a variety of age-related diseases.

Cellular senescence may play an important role in tumor suppression, wound healing, and protection against tissue fibrosis; however, accumulating evidence that senescent cells may have harmful effects in vivo and may contribute to tissue remodeling, organismal aging, and many age-related diseases also exists

Effectively, the process of senescence is synonymous with cell ageing, and for simplicity we can assume that inducing cellular senescence will promote accelerated ageing. With caveats, there appears to be a plus side to that: potential tumour suppression. Indeed, pharmaceutical research is interested in that. But nothing is ever that simple, and as Gonzalez-Meljem et al. point out in Paracrine roles of cellular senescence in promoting tumourigenesis, it’s a double-edged sword:

 Although senescence has historically been considered a protective mechanism against tumourigenesis, the activities of senescent cells are increasingly being associated with age-related diseases, including cancer. An important feature of senescent cells is the secretion of a vast array of pro-inflammatory cytokines, chemokines, and growth factors collectively known as the senescence-associated secretory phenotype (SASP). Recent research has shown that SASP paracrine signalling can mediate several pro-tumourigenic effects, such as enhancing malignant phenotypes and promoting tumour initiation.

What of the mechanisms and why are they important for us to know? In Management of multicellular senescence and oxidative stress  Haines & colleagues explain:

The first stage of cellular senescence is damage-induced cell cycle arrest, also called replicative senescence (RS). Typically, this growth arrest is triggered by stress-induced DNA damage responses (DDR), and also may be induced as a result of effects of telomere erosion – a phenomenon that produces stress-related metabolites 27.

From the above we clearly see that certain stressors can cause damage to DNA that induce responses in the cell that can lead to the cell cycle arrest. Because DNA damage can lead to cancer, attempting to ‘switch it off’ (cycle arrest) may be a good idea. Of course, when cellular senescence happens on a larger scale, as stressors accrue over time, it is recognised as ageing.

But what of vaccination?

In SARS-CoV-2 Spike Protein Induces Paracrine Senescence and Leukocyte Adhesion in Endothelial Cells, Meyer & colleagues explore a relationship of cellular senescence and virus SARS-CoV-2 infected cells. Their findings are concerning:

Virus-infected or spike-transfected human epithelial cells exhibited an increase in senescence, with a release of senescence-associated secretory phenotype (SASP)-related inflammatory molecules.

Source: SARS-CoV-2 Spike Protein Induces Paracrine Senescence and Leukocyte Adhesion in Endothelial Cells

The key point is that both SARS-CoV-2 virus infected cells and spike protein transfected cells induce cellular senescence.

That is troubling considering we are currently in a global campaign to vaccinate up to three or more doses to all ages, barring the very young, and all indications are they also will be vaccinated. And those vaccinations will be given repeatedly each year. All of which, per dose, produce in the order of billions or trillions of spike proteins. And remembering that animal studies demonstrated efficient distribution of the vaccine carriers (of the mRNA to produce those spike proteins) by varying amounts throughout the body, this is a serious concern.

But let us continue with another paper released recently: Integrated Stochastic Model of DNA Damage Repair by Non-homologous End Joining and p53/p21- Mediated Early Senescence Signalling, where Yang & Mei demonstrated another part of the puzzle:

 To determine how the spike protein inhibits both NHEJ and HR repair pathways, we analyzed the recruitment of BRCA1 and 53BP1, which are the key checkpoint proteins for HR and NHEJ repair, respectively. We found that the spike protein markedly inhibited both BRCA1 and 53BP1 foci formation (Figure 3D–G). Together, these data show that the SARS–CoV–2 full–length spike protein inhibits DNA damage repair by hindering DNA repair protein recruitment.

That was a bench study using cell models that demonstrated full length spike protein was expressed in the nucleus of the cell. It is important to note that spike protein should not be found in the VIP compartment of the cell – the nucleus.

Once there, the spike protein prevented other proteins, for example BRCA1, from being recruited for NHEJ repair – preventing repair of damaged DNA. Now, the body has back-up mechanisms, but we know from oncology that damage to key proteins such as BRCA1 lead to significant increase in cancer risk and shortened life-span.

The literature demonstrates that DNA damage left unrepaired or not repaired properly can also lead to cellular senescence.  Gerasymchuk, in Genome Stability (Second Edition), 2021 writes:

[P]ostmitotic cells rely on NHEJ for repairing DSBs. Failure to faithfully repair DSBs can result in point mutations, deletions and large genome rearrangements. 

Where else could this be a serious problem? Mitosis.

Mitosis is cell division that is a vital part of repair, growth and embryo development.

Mitosis is a type of cellular division where the cell divides into two equal halves. This type of division is very important in fetal development as this forms the basis of embryology.

With nanoparticles up to 500nm being taken up by the placenta, and Covid19 vaccine lipid nanoparticles being in the order of 60-100nm, what of the risk to the developing foetus if it crosses the placenta and gains access to the developing foetus?

What we are witnessing here is burgeoning evidence of spike protein-induced DNA damage and cellular senescence, with all their related sequelae and consequences: dysfunctional cellular repair, cancer and premature ageing – death.

The adage Sola dosis facit venenum or the dose makes the poison is a basic tenet in toxicology, and will be no different here with Covid vaccines. Apart from all the other serious effects that have already been demonstrated as a result of vaccination heavily implicating spike protein, repeatedly dosing human beings with Covid 19 vaccines, potentially inhibiting DNA repair and causing cellular senescence, with the attendant risks of cancer and decreased life-span do not bear thinking about. In the case of the developing foetus, would that risk entail never having a life to span?

All the above is deeply concerning because the bench work is being done now revealing those serious problems; why wasn’t that basic science done before the release of the vaccines?

As we close this discussion on cellular senescence, analysis of the currently available all cause mortality reveals a death rate amongst the vaccinated twice that of the unvaccinated.

Source: ONS Deaths by vaccination status, England – 2nd January to 24th September, 2021.

I chose all cause rather than the Covid data due to the unreliability of Covid data. All cause mortality is much cleaner and less corruptible. As it is age standardised and expressed as per 100,000, it removes a lot of the normal confounders.

Those data are very worrying coming from legitimate scientific work both from the laboratory and pure statistical analysis. Mechanisms are now being discovered that may help explain the paradoxical results of mass Covid 19 vaccination as partly evidenced by the all cause mortality data.

Sola dosis facit venenum  – the dose makes the poison

Or, more aptly, Consectetuer est venenum – the dose IS the poison.




The Liberty Beacon Project is now expanding at a near exponential rate, and for this we are grateful and excited! But we must also be practical. For 7 years we have not asked for any donations, and have built this project with our own funds as we grew. We are now experiencing ever increasing growing pains due to the large number of websites and projects we represent. So we have just installed donation buttons on our websites and ask that you consider this when you visit them. Nothing is too small. We thank you for all your support and your considerations … (TLB)


Comment Policy: As a privately owned web site, we reserve the right to remove comments that contain spam, advertising, vulgarity, threats of violence, racism, or personal/abusive attacks on other users. This also applies to trolling, the use of more than one alias, or just intentional mischief. Enforcement of this policy is at the discretion of this websites administrators. Repeat offenders may be blocked or permanently banned without prior warning.


Disclaimer: TLB websites contain copyrighted material the use of which has not always been specifically authorized by the copyright owner. We are making such material available to our readers under the provisions of “fair use” in an effort to advance a better understanding of political, health, economic and social issues. The material on this site is distributed without profit to those who have expressed a prior interest in receiving it for research and educational purposes. If you wish to use copyrighted material for purposes other than “fair use” you must request permission from the copyright owner.


Disclaimer: The information and opinions shared are for informational purposes only including, but not limited to, text, graphics, images and other material are not intended as medical advice or instruction. Nothing mentioned is intended to be a substitute for professional medical advice, diagnosis or treatment.

1 Comment on Revealed: The Vaccines Induce Cellular Ageing

Comments are closed.